Eddie Vedder has officially released a pair of new singles, “Matter of Time” and “Stay Hi”, which he debuted during a virtual charity event on Wednesday night.

The event, Venture Into Cures, was a benefit for the EB Research Partnership, the nonprofit Vedder and his wife, Jill Vedder, co-founded to help find a cure for epidermolysis bullosa, a genetic skin disorder. Per Rolling Stone, “Kids with EB are born with fragile skin and are subject to severe pain, external and internal wounds, and must undergo a rigorous bandaging process every day.”

Both of the new songs premiered by the Pearl Jam frontman during the event fall in line with the benefit’s mission. “Say Hi”, an acoustic guitar-focused song that’s been a part of Vedder’s live rotation for several years, was initially written for a young boy named Eli Meyer suffering from junctional epidermolysis bullosa. Today’s single drop marks the first time the song has been officially released.

“Matter of Time” trades the guitar for an emotional piano accompaniment as its driving force. On this one, Vedder more directly references the disease (“Still times when nothing’s alright / As we bandage up all our parts”) as it builds to a hopeful climax: “You got the cure, I’ll fight the fight / It’s just a matter of time.” The song was shared on Thursday along with a water color-style animated video in which kids with EB finally are able to remove their bandages to run off and play.

Below, you can watch the Watch Eddie Vedder perform “Say Hi” for Venture Into Cures and check out the new music video for “Matter of Time”. You can also stream both tracks via Spotify.

Eddie Vedder – “Say Hi” (Official Live Performance)

[Video: Eddie Vedder]

Eddie Vedder – “Matter of Time” (Official Video)

[Video: Eddie Vedder]

Eddie Vedder – “Matter of Time / “Say Hi”

Led by EBRP co-founders Jill and Eddie Vedder, Venture Into Cures featured uplifting stories of individuals with EB and their families along with appearances and performances by celebrity friends Judd Apatow, Jon Batiste, Alessia Cara, Bradley Cooper, Andra Day, Laura Dern, Billie Eilish, Glen Hansard, Chris Hemsworth, Jimmy Kimmel, David Letterman, Adam Levine, Gaten Matarazzo, Keb’ Mo’, Lukas Nelson & Promise of the Real with Micah, & Willie Nelson, Luis “King Kong” Ortiz, Adam Sandler, and Renée Zellweger. For more information on EBRP and Venture Into Cures, head here.